Spybot - Search & Destroy... FTW!
Once installed, choose updates, click search, tick everything that appears in the main window, choose Server "Safer Networking #2", choose "Download updates", choose "immunize", click the TOP immunize option, choose "Search & Destroy", choose "Search for Problems", choose "Fix all Problems". Do this roughly once a week. More if you browse pr0n.
Best AV program currently on the market?
---> Bullguard Antivirus. Most discrete, highest fix ratio and the best support for unknown/new viruses.
80% of my 40hour working week is
entirely spent on fixing Spyware and Virused infected PCs. I've tried every combination and piece of software on the market. Right now these 2 are the best...
(and no Bullguard's nothing to do with those other crappy swines

)