You should try it before saying too much about it.
Well you did ask if people would be interested in playing the mod or not.
I can see the appeal in it, but people's idea of what challenging is differs from player to player. Challenging for me would be finding it very difficult to survive even with health regen, have having zero health regen, not even a little from food just doesn't appeal to me, I would just find it kind of irritating. However food being very scarce would appeal to me, as you would have to find a decent amount of it to regain health anyway.