Oh yeah, A Vampyre Story - forgot about that one. It seems as if it might be an even better comeback for witty and funny adventure games a la Lucasarts than the big return of Sam & Max.
Of course it will come out - this year - the devs said it on the official forums and they even had a mostly functional preview version last fall... Their major problem seems to be finding a publisher - they had to switch like thrice but I think they'll be OK with Ascaron now...
http://www.jolt.co.uk/index.php?articleid=11525
It's true that Tim Schafer is a friggin' genius as well. I'll send a commando of assassin hamsters after everybody who hasn't played or bought Psychonauts - just like 
Ben 'Yahtzee' Croshaw... It almost ended up being a failure despite very good reviews and lots of awards until Double Fine switched to digital channels like Steam (thanks, Valve! You always appreciate the brilliant underdogs =)... It's a pity that Brütal Legend is only coming out on consoles... I guess it's because of the problems with publishing and marketing Psychonauts...